週次 |
日期 |
單元主題 |
第1週 |
9/17 |
Introduction |
第2週 |
9/24 |
Structural and Chemical Properties of Biological Macromolecules |
第3週 |
10/1 |
Protein Crystallography |
第4週 |
10/8 |
Principle of Nuclear Magnetic Resonance Spectroscopy |
第5週 |
10/15 |
Biomolecular NMR technique |
第6週 |
10/22 |
Multi-dimesional NMR for protein determination |
第7週 |
10/29 |
Biophysical Methods to Probe Non-covalent Molecular Interaction (I):Circular Dichroism, UV and Fluorescence Spectroscopy |
第8週 |
11/5 |
Biophysical Methods to Probe Non-covalent Molecular Interaction (II):Surface Plasmon Resonance and ITC |
第9週 |
11/12 |
Mid-term |
第10週 |
11/19 |
Structural Basis of Signal Transduction and Post-translation Modification |
第11週 |
11/26 |
Molecular Enzymology |
第12週 |
12/3 |
Protein/peptide interaction with membrane |
第13週 |
12/10 |
Structural Features of Receptors and ligands |
第14週 |
12/17 |
Structural View of Protein-DNA Recognition in Gene Regulation |
第15週 |
12/24 |
Analytical Ultracentrifugation |
第16週 |
12/31 |
Molecular Docking and Bioinformatics Approach |
第17週 |
1/7 |
Strategies for Drug Discovery, Rational Drug Design versus Drug screen |
第18週 |
1/14 |
final-exam |